The resins consist of aggregations of big insoluble molecules carrying fixed negative charges, which loosely bind positively charged ions (cations) these readily exchange with cations in the fluid environment to an extent that depends on their affinity for the resin and their concentration. O'Shaughnessy, in Clinical Pharmacology (Eleventh Edition), 2012 Cation-exchange resinsĬation-exchange resins are used to treat hyperkalaemia by accelerating potassium loss through the gut, especially in the context of poor urine output or before dialysis (the most effective means of treating hyperkalaemia).
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